Commercial Real Estate in Santa Fe, New Mexico

Browse 204 commercial real estate in Santa Fe, New Mexico (NM) with an average asking rent of $22 per SF, an average asking sale price of $338 per SF, and an average size of 7,393 SF.

Current Inventory204
Average Available Size7,393 SF
Total Available Size1.2M SF
Average Asking Price—
419 Orchard Dr listing image
Sale Multifamily

419 Orchard Dr

419 Orchard Dr, Santa Fe, NM 87501

  • $1.5M
  • 2,444 SF building
  • 0 ac

Real Estate Advisors, LLC is pleased to offer for sale 417, 417½ and 419 Orchard Drive, two adobe buildings on ±14,531 square feet of land in downtown Santa Fe. The two lots share one tax parcel and a large graveled parking area with access from both Orchard Drive and Paseo de Peralta.Both buildings date to 1950. 417 and 417½ is a duplex, both units are 1 bed 1 bath. 419 is a single familyresidence with an attached garage. Each propertyhas a full kitchen and full bath. One unit in 417is currently used as anoffice.BCD zoning allows a broad range of office and commercial uses, subject to city review. The offering will appeal to short term rental ownership, businesses who want a downtown address with its own parking, and to an investor looking for a cash flowing asset.

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2884 Trades West Rd listing image
Lease Industrial

2884 Trades West Rd

2884 Trades West Rd, Santa Fe, NM 87507

  • $14 SF/year
  • 2,000 SF
  • 15,876 SF building
  • 1 ac

Available Units:±1,000 SF (Unit F)±2,000 SF (Unit G)Can be Combined for 3,000 SFFlexible sizing — lease one unit or both$14/SF + NNN | 3-Year Term | I-2 ZoningPlug-and-play industrial units in Santa Fe's most active industrial corridorGrade-level roll-up doors make loading and logistics a breeze (10x10 & 16x10)11'–15' clear heights accommodate a wide range of industrial and contractor usesAmple parking with easy ingress/egressNeighbors include a thriving mix of trades, craft, and commercial service businesses Perfect For:Contractors and trades professionals needing a functional home baseLight manufacturing or fabrication operationsWarehousing, storage, or last-mile distributionCreative or maker-space users looking for an established industrial communityLocation Perks:Situated in the heart of the Trades West/Siler Road industrial hubMinutes from Walmart, Home Depot, Ace Hardware, and major retail amenitiesQuick access to US-285 and NM-599

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1281 Clark Road listing image
Sale/Lease LandIndustrial

1281 Clark Road

1281 Clark Rd, Santa Fe, NM 87507

  • $690K
  • $4K Month
  • 85,290 SF
  • 2 ac

Great for equipment storage, a contractor's yard, small or large warehouse development. The entire perimeter of this property is lined with high concrete walls for security and privacy. Good access and a central location. Secure, heavy metal entry gate. Electric transformer on-site (480 V, likely 3-Phase). Lots of concrete surface plus sufficient open ground (dirt) Cerrillos Rd to Siler, turn north on Trades West. Subject is at the intersection of Clark and Trades West.

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1701 Calle Medico listing image
Lease Office

1701 Calle Medico

1701 Old Pecos Trail, Santa Fe, NM 87505

  • Negotiable
  • 2,706 – 18,443 SF
  • 18,433 SF building
  • 7 Spaces

Suites may be combined for full-floor or multi-floor users. Usable SF is the area inside each suite's wall.Locally Owned & Professionally managedConveniently located minutes away from I-25, Santa Fe Plaza, various amenities, and the Medical CorridorNatural Lighting available in most suitesCommunity of local and national office tenantsIn close proximity to prominent medical, retail and office usersCampus visibility from Old Pecos TrailAmple parking for staff and visitorsBuilding Signage availableC-1 Zoning

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Baymont by Wyndham Santa Fe, NM listing image
Sale Hospitality

Baymont by Wyndham Santa Fe, NM

4150 Cerrillos Rd, Santa Fe, NM 87507

  • $4M
  • 54,556 SF building
  • 1 ac

Do not disturb Operator or Staff, see broker for more information.Tammen Hospitality Partners is pleased to present the Baymont by Wyndham Santa Fe, a 51 key limited service hotel on Cerrillos Road, Santa Fe's primary commercial corridor. The two story, interior corridor building sits on 1.26 fee simple acres adjacent to Santa Fe Place regional mall, with 72 surface parking spaces, pool, fitness center and business center. Ownership completed approximately $1,000,000 in capital improvements in 2025. The hotel currently holds rate parity with its competitive set while capturing well below its fair share of occupancy, leaving a clearly defined path to revenue growth through active sales management and brand repositioning. Santa Fe demand is anchored by state government and the 60 day 2027 legislative session, CHRISTUS St. Vincent Regional Medical Center, Los Alamos National Laboratory contractor travel, and year round cultural tourism. No new hotel supply is scheduled to deliver in the submarket before 2028.https://www.tammenhospitality.com/exclusive-listings?propertyId=baymontsantafe Investment HighlightsDual-Brand Conversion Potential: Spark by Hilton and City Express by Marriott Recent Renovation: Completed in 2024 Proven Rate Premium: Hotel has historically commanded ADR above its competitive set Occupancy Upside: Meaningful unclaimed share inside the existing competitive set Government Demand Available: State capital and 2027 legislative session business to capture Below Replacement Cost: Fee simple midscale priced well inside new-build economics Limited Near-Term Supply: Nothing in the submarket pipeline delivers before 2028 Property & Location HighlightsCerrillos Road Corridor: Positioned on Santa Fe’s primary commercial corridor near Santa Fe Place regional mall at 4250 Cerrillos Road, with quick I-25 access and a direct run to the historic Plaza. Efficient Physical Plant: Two-story interior-corridor masonry building on 1.26 acres with 72 surface spaces, pool, fitness center and business center. State Capital Demand: New Mexico’s seat of government, with a 60-day legislative session convening January 19, 2027. Regional Medical Anchor: CHRISTUS St. Vincent, Northern New Mexico’s only full-service health system, with 200 licensed beds and more than 2,300 associates. Cultural Tourism Base: Meow Wolf sits in the hotel’s own zip code, with the Plaza, Canyon Road, Santa Fe Opera and Indian Market driving year-round leisure demand. Positive Recent Trend: July 2026 RevPAR grew 12.5% while the competitive set declined 6.5%, a 15-point gain in RevPAR Index. 

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Retail Space Available – El Mercado Plaza listing image
Lease Retail

Retail Space Available – El Mercado Plaza

511 W Cordova Rd, Santa Fe, NM 87505

  • Negotiable
  • 1,063 – 5,004 SF
  • 5 Spaces

AVAILABLE: Unit 533:  ±1,135 SF, Unit 531: ±1,063 SF, Unit 525: ±1,616 SF, Unit 527-B: ±1,190 SF | LEASE RATE: See Advisors | ZONING: SC-2, Planned Shopping Center | HIGHLIGHTS: Establish shopping center, Ample customer parking, Excellent visibility and co-tenancy, Easy access via Cordova Rd., Don Diego Ave. & Camino de los Marquez, Nearby retailers include: CVS, Trader Joe’s, O’Reilly Auto Parts, Orange Theory, Sports Shops, Restaurants/Bakeries, State Departments and private, offices

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