Commercial Real Estate for Sale in Santa Fe, New Mexico

Browse 133 commercial real estate for sale in Santa Fe, New Mexico (NM) with an average asking sale price of $336 per SF and an average size of 13,302 SF.

Current Inventory133
Average Available Size13,302 SF
Total Available Size425.7K SF
Average Asking Price$2,181,500
1254 Calle de Comercio listing image
Sale/Lease Industrial

1254 Calle de Comercio

1254 Calle de Comercio, Santa Fe, NM 87507

  • $1.1M
  • $15.5 SF/year
  • 6,611 SF
  • 6,611 SF building
  • 1 ac

Rufina Industrial Park does not give up buildings like this often. 1254 Calle de Comercio is a free standing office and warehouse with 6,611 square feet on the ground floor and a 920 square foot mezzanine, set on a half acre in the Siler industrial area less than a quarter mile north of Cerrillos Road. It delivers vacant on October 1, 2026.The building does two jobs at once. There are 3,020 square feet of finished office at the front and 3,591 square feet of warehouse behind, served by drive-in overhead doors, with the mezzanine adding room above the floor. A contractor, supplier, fabricator or service company can run the office and the shop from one address.The site earns its keep as well. With 116 feet of frontage on Calle de Comercio and 29.1 percent site coverage, roughly seventy percent of the half acre is open for paved parking and fenced yard. Yard space ranks among the most sought after features in a Santa Fe market that has long been short of light industrial product.Construction combines frame and pre-engineered steel, with stucco and metal exterior walls on a concrete slab. The office section carries a built-up tar and gravel roof and the warehouse a pitched metal roof. Heating and cooling run on mini split systems under ten years old. Zoning is I-1, Light Industrial, intended for light manufacturing, processing, storage, warehousing, distribution and commercial uses. The site lies in FEMA Flood Zone X and is served by public water, sewer, electric and gas.Available for occupancy now. An owner user can close and occupy, or a tenant can take the whole building on a term. 6,611 SF free standing office and warehouse plus a 920 SF mezzanine, offered whole3,020 SF finished office and 3,591 SF warehouse0.522 acre site with 116 feet of frontage and 29.1 percent coverageFenced yard and paved on-site parkingDrive-in overhead doors serving the warehouseMini split heating and cooling, under ten years oldPitched metal roof over the warehouse, built-up roof over the officeI-1 Light Industrial zoning3 Phase PowerPublic water, sewer, electric and gasDelivers vacant October 1, 2026, immediate possessionUnder a quarter mile to Cerrillos Road, about 4.5 miles to Interstate 25

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419 Orchard Dr listing image
Sale Multifamily

419 Orchard Dr

419 Orchard Dr, Santa Fe, NM 87501

  • $1.5M
  • 2,444 SF building
  • 0 ac

Real Estate Advisors, LLC is pleased to offer for sale 417, 417½ and 419 Orchard Drive, two adobe buildings on ±14,531 square feet of land in downtown Santa Fe. The two lots share one tax parcel and a large graveled parking area with access from both Orchard Drive and Paseo de Peralta.Both buildings date to 1950. 417 and 417½ is a duplex, both units are 1 bed 1 bath. 419 is a single familyresidence with an attached garage. Each propertyhas a full kitchen and full bath. One unit in 417is currently used as anoffice.BCD zoning allows a broad range of office and commercial uses, subject to city review. The offering will appeal to short term rental ownership, businesses who want a downtown address with its own parking, and to an investor looking for a cash flowing asset.

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1281 Clark Road listing image
Sale/Lease LandIndustrial

1281 Clark Road

1281 Clark Rd, Santa Fe, NM 87507

  • $690K
  • $4K Month
  • 85,290 SF
  • 2 ac

Great for equipment storage, a contractor's yard, small or large warehouse development. The entire perimeter of this property is lined with high concrete walls for security and privacy. Good access and a central location. Secure, heavy metal entry gate. Electric transformer on-site (480 V, likely 3-Phase). Lots of concrete surface plus sufficient open ground (dirt) Cerrillos Rd to Siler, turn north on Trades West. Subject is at the intersection of Clark and Trades West.

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Baymont by Wyndham Santa Fe, NM listing image
Sale Hospitality

Baymont by Wyndham Santa Fe, NM

4150 Cerrillos Rd, Santa Fe, NM 87507

  • $4M
  • 54,556 SF building
  • 1 ac

Do not disturb Operator or Staff, see broker for more information.Tammen Hospitality Partners is pleased to present the Baymont by Wyndham Santa Fe, a 51 key limited service hotel on Cerrillos Road, Santa Fe's primary commercial corridor. The two story, interior corridor building sits on 1.26 fee simple acres adjacent to Santa Fe Place regional mall, with 72 surface parking spaces, pool, fitness center and business center. Ownership completed approximately $1,000,000 in capital improvements in 2025. The hotel currently holds rate parity with its competitive set while capturing well below its fair share of occupancy, leaving a clearly defined path to revenue growth through active sales management and brand repositioning. Santa Fe demand is anchored by state government and the 60 day 2027 legislative session, CHRISTUS St. Vincent Regional Medical Center, Los Alamos National Laboratory contractor travel, and year round cultural tourism. No new hotel supply is scheduled to deliver in the submarket before 2028.https://www.tammenhospitality.com/exclusive-listings?propertyId=baymontsantafe Investment HighlightsDual-Brand Conversion Potential: Spark by Hilton and City Express by Marriott Recent Renovation: Completed in 2024 Proven Rate Premium: Hotel has historically commanded ADR above its competitive set Occupancy Upside: Meaningful unclaimed share inside the existing competitive set Government Demand Available: State capital and 2027 legislative session business to capture Below Replacement Cost: Fee simple midscale priced well inside new-build economics Limited Near-Term Supply: Nothing in the submarket pipeline delivers before 2028 Property & Location HighlightsCerrillos Road Corridor: Positioned on Santa Fe’s primary commercial corridor near Santa Fe Place regional mall at 4250 Cerrillos Road, with quick I-25 access and a direct run to the historic Plaza. Efficient Physical Plant: Two-story interior-corridor masonry building on 1.26 acres with 72 surface spaces, pool, fitness center and business center. State Capital Demand: New Mexico’s seat of government, with a 60-day legislative session convening January 19, 2027. Regional Medical Anchor: CHRISTUS St. Vincent, Northern New Mexico’s only full-service health system, with 200 licensed beds and more than 2,300 associates. Cultural Tourism Base: Meow Wolf sits in the hotel’s own zip code, with the Plaza, Canyon Road, Santa Fe Opera and Indian Market driving year-round leisure demand. Positive Recent Trend: July 2026 RevPAR grew 12.5% while the competitive set declined 6.5%, a 15-point gain in RevPAR Index. 

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Multi-Purpose Space with Yard listing image
Sale Industrial

Multi-Purpose Space with Yard

2917 Rufina Ct, Santa Fe, NM 87507

  • $410K
  • 989 SF building
  • 0 ac

AVAILABLE: Building: ±989 SF, Land: ±0.17Ac. | SALE PRICE: $410,000 | ZONING: I-2, General Industrial | HIGHLIGHTS: A hard-to-find zoning property, Centrally located, Accessible by major roads, Lots of natural lights, 7’ H x 8’ W overhead door, 10’ ceiling height, Possible uses: Warehousing, Storage facility, Manufacturing, Auto repair/Body shop, Commercial kitchen, Light or heavy industrial uses, Tenant in place. See advisor for more details

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1464 S St Francis Dr listing image
Sale Office

1464 S St Francis Dr

1464 S St Francis Dr, Santa Fe, NM 87505

  • $209K
  • 1,176 SF building

Desirable two-story office condo for sale in the Saint Francis Professional Center (Clock Tower). The space features four windowed offices, one with a charming kiva fireplace and two with built-in bookcases. It also includes a private restroom, a spacious waiting/reception area with ample storage, and newly installed commercial-grade carpet throughout. Conveniently located just off South St. Francis Drive, the property offers easy access to I-25, restaurants, and shopping. Condo dues are approximately $573 quarterly. A great opportunity for a small business or satellite office. On St. Michaels Dr and South St. Francis Dr. head North for approx. 0.5 miles. Turn left at the St. Francis. Professional Center clock tower entrance. Turn right at the end of the road and building is on the left hand side of the street.

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